16^th Global Diabetes Conference and Medicare Expo March 22-23, 2017 Rome, Italy

Diabetes may be analysed based on both plasma glucose criteria or  A1C criteria. Early in disease diabetes shows no symptoms so blood tests are used to diagnose diabetes and pre-diabetes. Clinical diagnostic in diabetes involve taking blood at a healthcare facility centre or commercial diagnostic centre and sending the sample to a lab for examination. To ensure that test results are accurate lab study of blood of required. Glucose calculating devices used in a health care provider’s office, such as finger-stick devices, are not precise enough for analysis but may be used as a rapid indicator of high blood sugar. Such area of research are highle discussed in  ADA annual meeting  and ADA sessions.

Diabetes case reports are in-depth inquiries of an individual, crowd, occasion or public. The data are assembled from a diversity of places by various methods.The case study technique encompasses spotting what happens to, or reconstructing ‘the case history’ of a single participant or group of individuals, i.e the idiographic approach. Case studies permits an investigator to investigate a topic in far more detailed and minute way.The case study is not itself a research method, but investigators choose methods of data collection and analysis that will generate material suitable for case studies. Most of this evidence is likely to be qualitative but the psychologist might collect numerical data as well and present in various diabetes conference and scientific sessions

Diabetes is a severe illness that cannot be cured of its own. Doctor aids to create a diabetes management plan that is right for the patient. Cure for diabetes demands to keep close watch over the blood sugar level with a combination of medications, work out, and diet. Since the spectacular finding in Toronto in 1922 that type 1 diabetes arises from a deficit of insulin. Research on Insulin is extensively discussed in National Diabetes Conference and Diabetes associations.The supervision of diabetes has been decisively grounded in scientific advances that endure to outline our understanding of the pathophysiology of diabetes  and direct our choices in choosing optimal therapies for type 1 and type 2 diabetes. Now, a days we get in market glucose meters which is a modern technology which has the capability to help people living with type 1 or type 2 diabetes and treated with insulin to accomplish the dream of ideal control of blood sugar.

Diabetes trade directs to the 11 largest therapeutic and diagnostic companies producing diabetes related merchandises or those involved with to take diabetes cure to next level. Diabetes is a major issue in the UK, and as such a large healthcare and medical industry has come up like mushroom around it. Aspects such as growing number of diabetic patients across BRIC countries, increasing study on diabetes, and increasing international research collaborations are lashing the growth of the this market. In the European Region there is about 60 million people leaving with diabetes, or about 10.3% of men and 9.6% of women aged 25 years and over. Occurrence of diabetes is growing among all ages in the, typically due to escalations in overweight and obesity, unhealthy diet and less of physical activity.

Complementary and alternative medicine is can be well-defined as a "cluster of varied therapeutic and health care arrangements, practices, and medicines that are not presently measured to be part of predictable medicine”. Complementary medicine is used with predictable therapy, whereas alternative medicine is used instead of conventional medicine. In CAM therapies diabetes supplement is widely given to the diabetic patients in. Although some of these therapies may be useful, others can be not so useful or even harmful. Contrary reactions of many CAM therapies are not well known because patients with diabetes often take various diabetes medications, there occurs budding for herbal medicine and herb dietary habit supplement interactions, leading to contrary events.

Molecular Biomarkers can be demarcated as “a characteristic that is accurately measured and gauged as an pointer of normal biological procedures, pathogenic procedures, or pharmacologic responses to a pharmaceutical intervention. Biomarkers play an vital part in leading clinical trials and treating patients. Advances in molecular diagnostics help medical professionals make knowledgeable, scientifically valid decisions. More well-organized discovery and usage of biomarkers in the growth of antidiabetes drugs will depend on accelerating our understanding of the pathogenesis of diabetes and specifically its macrovascular complications.  Procedural improvements from other fields, especially cancer, are beginning to show the way towards better models of diabetes pathogenesis and molecular biomarker discovery.

Clinical Endocrinology and metabolism is a field of medicine; more precisely a sub-specialty of internal medicine, which mainly deals with the investigation and management of sicknesses related to hormones. The human endocrine system involves number of glands. These glands harvest and release hormones which monitors many important function of our body. When the hormones exits the glands they arrive the bloodstream and are moved to organs and tissues in every part of the body. Endocrinology also concentrates on the endocrine glands and tissues that secrete hormones. The human endocrine system comprises of several glands. These glands harvest and secrete hormones which regulates the body's metabolism, growth, sexual development and function. Hormonal imbalance in our body henceforth leads to diabetes.

Long-standing complications of diabetes grow progressively. Number of years of having diabetes is directly proportional to the higher risk of complications. Sometimes diabetes complications may be restricting or even lethal. A well-controlled blood sugar have less diabetic complications.  Broader health issues quicken the venomous effects of diabetes which include smoking, higher diabetes cholesterol levels, obesity, high blood pressure, and lack of regular exercise. The best forecaster of type 2 diabetes is overweight or obesity. People who have weight related issues or have obesity have additional pressure on their body's capability to use insulin to properly control blood sugar levels, and are therefore pick up diabetes more easily.

Diabetes intensifies the danger of long-term complications. Diabetes increases the risk of cardiovascular diseases such as diabetic cardiomyopathy. The chief complications of diabetes due to injury in small blood vessels comprise damage to the eyes, kidneys, and nerves. Damage to the eyes is known as diabetic retinopathy which is triggered by damage to the blood vessels in the retina of the eye leading to diabetic eye complications. Damage to the kidneys, known as diabetic nephropathy, can pave the way to tissue damaging, urine protein damage, and eventually dibetic nephropathy disease. Diabetes is one of the main cause of kidney failure. At least two third of the people with diabetes may have signs of onset of kidney problems at early stage. Damage to the nerves of the body, known as diabetic neuropathy, is the most common complication of diabetes.

Metabolic syndrome and related metabolic traits heritability is relatively high. Genetically altered knockout mice models and human monogenic obese/insulin unaffected syndrome deliver significant molecular insights into the pathogenesis of the metabolic syndrome. Transfer (engraftment) of human cells, tissues or organs from a donor to a recipient with the aim of restoring function in the body is called as transplantation. It can be of various types such as pancreas transplantation, xenotransplantation and islet transplantation.

Cell therapy can be explained as the supervision of live whole cells or maturation of an exact cell population in a patient to overcome the disease. Cell therapy is growing its range of cell types for administration. The treatment strategies of cell therapy comprise separation and transmission of specific stem cell populations, administration of effector cells, induction of mature cells to develop pluripotent cells, and reprogramming of mature cells.The founding of pluripotent human embryonic stem cells and embryonic germ cells have presented a new probable source in type 1 diabetic patients for cell therapy, especially in light of recent successes in generating glucose-sensitive insulin-secreting cells from mouse embryonic stem cells.

Diabetes care market encompasses of technologies, devices and therapeutics in relative to diabetes. There has been a substantial increase in the amount of diabetes cases internationally over the last few years. Currently, about millions of people are in misery because of obesity, which is a key reason for increase of diabetes in people. Key Players profiled in the report include Glaxosmithkline, Novo Nordisk, Roche, Medtronicand etc. Novo Nordisk is a leading global provider of diabetes products. The company also has a headship spot in hemostasis management, growth hormone therapy and hormone replacement therapy. The company progresses, manufactures and markets its medical devices and technologies to hospitals, doctors, researchers, scientists and patients in approximately 160 countries.

Diabetes throws a light in a growing epidemic imposing thoughtful social economic crisis around the nation. Despite scientific innovations and better healthcare research amenities the disease continues to burden numerous segments, especially middle and low income countries. The current trends designate the rise in premature death, posing a major threat to global development. The advancement in science and technology have observed the expansion of newer generation of nanomedicine in drugs discovery. Then, the documentation and clinical investigation of bioactive ingredients from plants have transformed the investigation on drug discovery and lead identification for diabetes management control.

Foot problems are a big risk. All people with diabetes should monitor their feet. If you don't, the consequences can be severe, including amputation. Minor injuries become major emergencies before you know it. With a diabetic foot, a wound as small as a blister from wearing a shoe that's too tight can cause a lot of damage. Diabetes may also decrease your blood flow, so your injuries can be slow to heal. If your wound is not healing, it's at risk for infection. As a diabetic, your infection may spread quickly, and if you have any loss of sensation (neuropathy) you may not recognize that the problem is getting worse. People whose diabetes is not properly controlled tend to have more foot problems than nondiabetics. Having diabetes is not a sentence to developing problems with the feet. Lifestyle and physical activity plays an important role. The patient’s profession can be an indicator to determine what their prognosis may be. Types of diabetic foot and ankle problems seen are multifactorial. The most common complication is peripheral neuropathy. It is often because patients with long-standing diabetes, who have diabetic peripheral neuropathy, may not have adequate feeling in one or both feet or ankles, to know early that something is wrong.

Being overweight increases the chances of developing the common type of diabetes, type 2 diabetes. In this disease, the body makes enough insulin but the cells in the body have become resistant to the salutary action of insulin. Science proposes that being overweight stresses the insides of individual cells. Specifically, overeating stresses the membranous network inside of cells called endoplasmic reticulum (ER). Most patients with type 2 diabetes are obese, and the global epidemic of obesity largely explains the dramatic increase in the incidence and prevalence of type 2 diabetes over the past 20 years. Currently, over a third (34%) of U.S. adults are obese (defined as BMI >30 kg/m2), and over 11% of people aged ≥20 years have diabetes, a prevalence projected to increase to 21% by 2050. Reducing your body weight, by even a small amount, can help improve your body's insulin sensitivity and lower your risk of developing cardiovascular and metabolic conditions such as type 2 diabetes, heart disease and types of cancer.

The metabolic syndrome is a cluster of the most dangerous heart attack risk factors: diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. People with metabolic syndrome have a five-fold greater risk of developing type 2 diabetes. Up to 80% of the 200 million people with diabetes globally will die of cardiovascular disease. This puts metabolic syndrome and diabetes way ahead of HIV/AIDS in morbidity and mortality terms.

During pregnancy – usually around the 24th week – many women develop gestational diabetes. Diabetes can be especially hard on women. The burden of diabetes on women is unique because the disease can affect both mothers and their unborn children. Expectant moms can help control gestational diabetes by eating healthy foods, exercising and, if necessary, taking medication. Controlling blood sugar can prevent a difficult birth and keep you and your baby healthy. Treating gestational diabetes can help both you and your baby stay healthy. You can protect your baby and yourself by taking action right away to control your blood glucose levels.

Insulin therapy is recommended for patients with type 2 diabetes mellitus and an initial A1C level greater than 9 percent, or if diabetes is uncontrolled despite optimal oral glycemic therapy. Insulin therapy may be initiated as augmentation, starting at 0.3 unit per kg, or as replacement, starting at 0.6 to 1.0 unit per kg. Glucose control, adverse effects, cost, adherence, and quality of life need to be considered when choosing therapy. Metformin should be continued if possible because it is proven to reduce all-cause mortality and cardiovascular events in overweight patients with diabetes. Titration of insulin over time is critical to improving glycemic control and preventing diabetes-related complications.

There are many myths about diabetes that make it difficult for people to believe some of the hard facts – such as diabetes is a serious and potentially deadly disease. These myths can create a picture of diabetes that is not accurate and full of stereotypes and stigma. Diabetes is an economic burden estimated at 3 billion dollars per year in direct and indirect costs. Diabetes threatens those we love. It is lived—and battled—every day by real people and families. It is treated by knowledgeable and caring doctors, nurses, diabetes educators and other health care professionals. Scientific researchers dedicate their careers to improving diabetes treatments and finding a cure.

There is a rising incidence and prevalence of diabetes mellitus. About 50% of people with diabetes mellitus are unaware of their condition. Approximately 25% of all patients with diabetes undergoing surgery are undiagnosed on admission to hospital. Patients with diabetes have a higher risk of cardiovascular disease. Patients with diabetes have a higher perioperative risk. They are more likely because of their disease to require surgery and those undergoing surgery are likely to be less well controlled and to have complications from their diabetes. Surgeons and anaesthetists operating on patients with diabetes should be familiar with the risks attached to having diabetes, and to the particular risks of the particular surgery and of anaesthesia in patients with diabetes.

People with diabetes have a higher chance of developing cardiovascular diseases. The term cardiovascular disease (CVD) includes heart disease, stroke and all other diseases of the heart and circulation. Blood vessels are damaged by high blood glucose levels, high blood pressure, smoking or high levels of cholesterol. A large body of epidemiological and pathological data documents that diabetes is an independent risk factor for CVD in both men and women. Because of the aging of the population and an increasing prevalence of obesity and sedentary life habits in the United Kingdom, the prevalence of diabetes is increasing. Thus, diabetes must take its place alongside the other major risk factors as important causes of cardiovascular disease (CVD).

Diabetic retinopathy is caused by changes in the blood vessels of the retina. When these blood vessels are damaged, they may leak blood and grow fragile new vessels. When the nerve cells are damaged, vision is impaired. These changes can result in blurring of your vision, hemorrhage into your eye, or, if untreated, retinal detachment. Diabetic retinopathy is the most common diabetic eye disease and a leading cause of blindness. People with untreated diabetes are 25 times more at risk for blindness than the general population. The longer a person has had diabetes, the higher the risk of developing diabetic retinopathy. Fortunately, with regular, proper primary eye care and treatment when necessary, the incidence of severe vision loss has been greatly reduced.

Diabetic nephropathy is damage to your kidneys caused by diabetes. In severe cases it can lead to kidney failure. The kidneys have many tiny blood vessels that filter waste from your blood. High blood sugar from diabetes can destroy these blood vessels. Over time, the kidney isn't able to do its job as well. Later it may stop working completely. This is called kidney failure. There are no symptoms in the early stages. So it's important to have regular urine tests to find kidney damage early. Sometimes early kidney damage can be reversed. The problem is diagnosed using simple tests that check for a protein called albumin in the urine.