Mohsen Khalid
Egyptian National Institute of Diabetes and Endocrinology, Egypt
Title: Study of metabolic and some hormonal aspects among pubertal type 1 diabetic girls
Biography
Biography: Mohsen Khalid
Abstract
The onset of type 1 diabetes before menarche was a risk factor for the subsequent development of hyperandrogenic disorders. It has been also suggested that the use of exogenous insulin to treat type 1 diabetes mellitus in those patients may contribute to the development of PCOS. Abnormal lipid levels were also reported in children with type 1 diabetes mellitus during pubertal years. Aim of Work: This study was designed to investigate metabolic and some hormonal changes in relation to puberty among type 1 diabetic girls. Subjects and Methods: The study was carried out on 60 girls, 40 of them were type 1 diabetic patients (the diabetic group), subdivided into 2 groups (according to age and Tanner breast staging) ,and 20 of them were normal healthy girls (the control group), also subdivided into 2 groups ( according to age and Tanner breast staging). All girls were subjected to full history taking, thorough clinical examination, estimation of fasting blood glucose and HbA1c (as an estimation for glycemic control), lipid profile, hormonal profile (FSH, LH and free testosterone) in addition to pelvic ultrasound