16^th European Diabetes and Endocrinology Congress

Genetics and Transplantation of Diabetes

Submit Abstract Register Now

The estimated heritability of the metabolic syndrome and related metabolic traits (including obesity, dyslipidemia, abnormal glucose regulation and elevated blood pressure) is relatively high. Genetically modified knockout mice models and human monogenic obese/insulin resistant syndrome provide important molecular insights into the pathogenesis of the metabolic syndrome. Transplantation is the transfer (engraftment) of human cells, tissues or organs from a donor to a recipient with the aim of restoring function in the body. Transplantation can be of various types such as pancreas transplantation, xenotransplantation and islet transplantation. A pancreas transplant is surgery to implant a healthy pancreas from a donor into a patient with diabetes.